UWinChem

Friday, November 17, 2017

Tenure-Track Assistant Professor Position in Biochemistry

Tenure-Track Assistant Professor Position in Biochemistry

Deadline Date: 
 Wednesday, January 03, 2018
The University of Windsor's Department of Chemistry and Biochemistry, in the Faculty of Science, invites applications for a tenure-track faculty position at the rank of Assistant Professor in the area of Biochemistry, commencing July 1, 2018. This position is subject to final budgetary approval.
The Department of Chemistry & Biochemistry has strong undergraduate and graduate programs, along with fundamental and applied research in Chemistry and Biochemistry.  Currently the Department has 22+ faculty and 11 support staff.  Research areas include: health-related biochemistry, environmental and protein chemistry, the preparation and characterization of advanced biomaterials, synthetic inorganic and organic chemistry, and solid-state chemistry.  Our research programs are funded by the national granting councils (NSERC, CIHR), industrial sponsors and private funding agencies (HSFC, CRS, Michael J. Fox Foundation, Seeds4Hope Foundation, etc.).  We have a Tier 1 Canada Research Chair among our talented contingent of faculty.  Our department is also home to the Center for Catalysis and Materials Research (CCMR) and actively participates in the Windsor Cancer Research Group http://www.uwindsor.ca/chemistry.
The ideal candidate must possess a PhD in Biochemistry, Chemical Biology, or related fields.  The incumbent is expected to establish a vibrant, externally funded research program in any area of experimental Biochemistry; however, exceptional candidates from other areas will also be considered. Significant financial resources and dedicated laboratory space are associated with this faculty position. The appointee will have access to state-of-the-art facilities for genomics, proteomics, biophysical characterization, imaging, NMR, X-ray, which will be located in a new Faculty of Science Research & Innovation Facility (Spring 2018 occupancy).
The candidate is expected to train graduate/undergraduate students and postdoctoral fellows, teach undergraduate and graduate courses in biochemistry, and participate in the delivery of our successful professional graduate programs. In addition, an outstanding record of research productivity, and a willingness to work in a highly collaborative and multidisciplinary research environment are expected.
Application Requirements
  • a letter of application, including a statement of citizenship/immigration status;
  • a detailed and current curriculum vitae;
  • two (2) page outline of research interests and accomplishments;
  • a draft NSERC Discovery Grant research proposal (up to 5 pages with 2 additional pages of references)
  • samples of scholarly writing (up to 3), including (if applicable) clear indications of your contribution to any jointly authored pieces;
  • a teaching dossier or teaching portfolio showing a potential for or evidence of teaching effectiveness and excellence that will include sample course syllabi/outlines, teaching evaluations, and a statement of teaching philosophy and interests (resources and templates for completing a teaching dossier can be found at http://www.uwindsor.ca/ctl/links-pd);
  • graduate transcripts; and
  • three (3) current letters of reference forwarded directly by the referees to the Head at the address or email listed below.
Only those applicants selected for interview will be contacted.  The short-listed candidates may be invited to provide further information in support of their applications.  To ensure full consideration, complete an online application found on the job advertisement (http://www.uwindsor.ca/facultypositions), and ensure letters of reference are submitted by the deadline date of January 3, 2018.  Applications may be considered after the deadline date; however, acceptance of late submissions is at the discretion of the appointments committee. 
When completing the online application, please reference:
Position Number: 002023TT-2018-CHE
Questions and Reference Letters to be sent to:
Dr. Charles Macdonald, Head, Department of Chemistry & Biochemistry,
University of Windsor 401 Sunset Avenue, Windsor, Ontario, Canada N9B 3P4,
Phone: 519-253-3000 Ext. 3526; Fax: 519-973-7098;
Email: chembiohead@uwindsor.ca
The University of Windsor is a comprehensive research and teaching institution with more than 15,500 students.  We are a welcoming community committed to equity and diversity in our teaching, learning, and work environments.  In pursuit of the University's Employment Equity Plan, members from the designated groups (Women, Aboriginal Peoples, Visible Minorities, Persons with Disabilities, and Sexual Minorities) are encouraged to apply and to self-identify.  If you need an accommodation for any part of the application and hiring process, please notify the Faculty Recruitment Coordinator (recruit@uwindsor.ca). Should you require further information on accommodation, please visit the website of the Office of Human Rights, Equity & Accessibility (http://www.uwindsor.ca/ohrea).  All qualified candidates are encouraged to apply; however, Canadians and permanent residents will be given priority.

Seminar: Prof. Robert Scott (University of Saskatchewan) - Friday, Nov. 17, 2017 @ 3:00 p.m. 186 Essex Hall

Seminar: Prof. Robert Scott (University of Saskatchewan)

UWinChemBiochem Seminar Series - Fall 2017


Dr. Robert Scott
Department of Chemistry
University of Saskatchewan
Title: Shining Light on Cluster and Nanoparticle Catalysts”
http://www.usask.ca/chemistry/groups/scott/

Friday, Nov. 17, 2017 @ 3:00 p.m.

Room #186 Essex Hall

**Everyone Welcome**





Abstract:

In this seminar, I will discuss work in our group focusing on the development of cluster and nanoparticle catalysts which have high catalytic activity, excellent selectivity towards specific substrates, and excellent durability and recyclability. Our current work involves the synthesis and stabilization of clusters and nanoparticles in solution followed by activating them for catalysis. Several routes towards such goals will be discussed, including the activation of monolayer-protected Au clusters and structural control of bimetallic nanoparticles. Characterization tools which can assist in elucidating surface chemistry and/or cluster and nanoparticle sizes and structures will be detailed, including mass spectrometry, HRTEM, and in situ x-ray absorption spectroscopy at the Canadian Light Source.

Thursday, November 9, 2017

Seminar: Prof. Kai Kessenbrock (University of California, Irvine) - Friday, Nov. 10, 2017 @ 3:00 p.m.

Seminar: Prof. Kai Kessenbrock (University of California, Irvine)

UWinChemBiochem Seminar Series - Fall 2017

Prof. Kai Kessenbrock 
Department of Biological Chemistry
School of Medicine 
http://kessenbrocklab.com/kai-kessenbrock/

Title: “The role of the microenvironment in epithelial tissue homeostasis and breast cancer”

Friday, Nov. 10, 2017 @ 3:00 p.m.
Room #186 Essex Hall

**Everyone Welcome**



Tuesday, November 7, 2017

Seminar: Dr. Preston Chase (Green Centre Canada) - Thursday, Nov. 9, 2017 @ 3:00 p.m. Room 311 Memorial Hall

Seminar: Dr. Preston Chase (Green Centre Canada)

UWinChemBiochem Seminar Series - Fall 2017


Dr. Preston Chase
Director of Academic Business Development
Green Centre Canada

https://www.greencentrecanada.com/about-us/people/commercial/preston-chase/

Title: Development and Commercial Application of Novel Catalyst and Forward Osmosis Technologies


Thursday, Nov. 9, 2017 @ 3:00 p.m.
Room 311 Memorial Hall

**Everyone Welcome**


***Note special seminar day and time***



Abstract:

Progressing academic research from the initial invention discovery at the bench to industrial application requires significant efforts, including, for example, scaling of materials for testing, development and validation of new systems of a base technology, and optimization of processes. GreenCentre Canada is a Centre of Excellence for Commercialization and Research in the area of Green Chemistry, providing facilities for both academic and industrial partners to evaluate, develop and ultimately find commercial application for novel Green chemical technologies.

To highlight the path towards industrial applications, three projects that have been advanced at GreenCentre will be presented: the development and scale-up of highly active ester hydrogenation catalysts, the immobilization of a number of homogeneous catalysts for application in flow reactors directed to pharmaceuticals generation, and the development and process optimization of a low energy forward osmosis process. Each will have the contribution of the original inventors and additional efforts of GreenCentre to directly address specific industry-based challenges highlighted.



ChemDraw Prime available for department members

University of Windsor  - ChemDraw Prime 17 for Windows & Macintosh is now available for members of our department, and the Annual Site Subscription has been renewed.

Go to http://www.uwindsor.ca/softwaredepot to get your license.

***Thanks to Joe Lichaa for this update!


Saturday, November 4, 2017

GA/TA Winter 2018 Job Postings - Deadline for Applications: Dec. 6, 2017

GA/TA Winter 2018 Job Postings - Deadline for Applications: Dec. 6, 2017

CLICK HERE for full information on these job postings

In accordance with Article 12:01 of the CUPE 4580 Collective Agreement the Department of Chemistry & Biochemistry invites applications for TA / GA positions for the WINTER term 2018. 

Courses include:
59-110
59-141
59-230
59-261

Applications must be submitted to: Beth Kickham in Essex Hall, Room 275-D.

Deadline for receiving applications: Wednesday December 6th, 2017 or until positions have been filled.

Note that Graduate Assistants must apply each term by the application deadline, in accordance with Article 13

Thursday, November 2, 2017

Seminar: Prof. Jean-Francois Morin (Laval University) - Fri. Nov. 3, 2017 @ 3 pm

Seminar: Prof. Jean-Francois Morin (Laval University)

UWinChemBiochem Seminar Series - Fall 2017


Prof. Jean-Francois Morin
Department of Chemistry
Université Laval Québec
http://labnanoorg.chm.ulaval.ca/en/about

Title: Structurally Precise Nanographenes and Graphene Nanoribbons: from Stable Biradicals to Carbon Nanotubes Wrapping

Friday, Nov. 3, 2017 @ 3:00 p.m.
Room #186 Essex Hall

**Everyone Welcome**

Tuesday, October 31, 2017

Jeopardy! Night - Presented by the Undergraduate Chem Club - Nov. 1, 2017 from 6-8 pm

Jeopardy! Night - Presented by the Undergraduate Chem Club - Nov. 1, 2017 from 6-8 pm

Doors Open 5:30 pm
Jeopardy! from 6:00 - 8:00 pm
Essex Hall Room 250

Open to all students, staff, and faculty for free!!




Monday, October 30, 2017

Grad Chem Club Halloween Party - Oct. 31 at 5 p.m.

Department of Chemistry & Biochemistry Researchers...

Come to the:

Grad Chem Club Halloween Party

October 31st, 2017, 5:00pm
Science Lounge 🕷 250 Essex Hall
$5.00 entry
includes pizza, desserts, 1 drink ticket
Costumes Encouraged!
Prizes for top 3 costumes!



Thursday, October 26, 2017

Biochemist to study how proteins contribute to neurodegenerative diseases

Biochemist to study how proteins contribute to neurodegenerative diseases


UWindsor biochemistry graduate student Cody Caba and professor Bulent Mutus display the crystal structure of protein disulfide isomerase. Mutus received an NSERC Discovery Grant to examine cell proteins and structures and how they contribute to diseases.

Bulent Mutus is a micro mechanic.

But instead of fixing cars with wrenches and grease, the biochemist rolls up his sleeves and chops up and rebuilds proteins using microscopes and Petri dishes.

“If this enzyme were a car we would know where the engine is, but now we are looking at turning that engine off so the pathology will go away,” the UWindsor professor said.

Dr. Mutus recently received a $100,000 Discovery Grant over five years from the Natural Sciences and Engineering Research Council of Canada (NSERC) to examine cell proteins and structures and how they contribute to diseases like cystic fibrosis and Alzheimer’s.

The human body is made up of about 10 trillion cells that intricately interact with one another to ensure the body functions properly. When cell-to-cell and internal cell signaling is disturbed, the body cannot function properly, and acute diseases and physiological or neurological disorders occur.

“It’s similar to a teeter-totter, wherein a normal situation everything is balanced,” Mutus explained.

Every cell contains strings of amino acid molecules that fold onto themselves, forming structures called proteins.


The crystal structure of protein disulfide isomerase is pictured in this computer visualization. 

“If there’s something that messes up the balance within the cell, then the proteins don’t fold properly, and you get something called unfolded protein response,” he said.

Diseases reactive to the unfolded protein response include Alzheimer’s, Parkinson’s and Huntington’s — as well as many others.

Proteins are encoded from DNA instructions and form in ways that allow them to combine with other substrates to perform work. When proteins do work, they are called enzymes and help the body to function properly.

Mutus’ NSERC research focuses on a sequence of amino acids containing sulfur, called cysteine amino acids, and the role they play in the regulation of enzymes. In the sequence, called the CXXC motif, two amino acids represented by the letter C for cysteine, are separated by any other two of the 23 amino acids, which are represented by X. These cysteine amino acids have a sulfur group that often binds to itself to create a stronger bond or fold within the protein structure.

Mutus said the sequence affects structure which in turn affects the function, and so improper sequences or structures can cause harmful pathologies in the body.

“Structure is related to function, and so if you build a building and you don’t have any doors it’s not going to be very functional,” the researcher said. “The same goes with a protein, and if a sequence works well in one particular protein, then it’s copied and repeatedly used somewhere else.”

By studying this CXXC protein sequence and its function in various cellular pathways, researchers can develop therapies to treat diseases caused by improper function.

Mutus’ lab has created probes that will bind to CXXC enzymes within the cells which can be followed to see their functions in internal cellular pathways.

He said an example of this is found in patients with cystic fibrosis. Within these patients, an enzyme called S-Nitrosoglutathione Reductase (GSNOR) is unable to form at appropriate levels in the lungs and can’t function in ion transport.

“If that ion transport protein can’t mature and enter into the cell membrane where it belongs, then fluid essentially starts to accumulate in the lungs and leads to infections,” Mutus said. “So if an enzyme contains this CXXC motif, and we think we can tweak onto something that’s a very small run of four or five amino acids, where we can play with one of the amino acids and really regulate the enzyme, like turning a car engine on and off to control negative pathologies in the body.”

Mutus’ research will eventually have implications in drug design as a means of controlling these important enzymes involved in pathologies and diseases that may affect all of us.

See the full story at the UWindsor Daily News

Monday, October 23, 2017

Seminar: Tony Durst (University of Ottawa) - Fri. Oct. 27, 2017 @ 3:00 p.m.

Seminar: Tony Durst (University of Ottawa)

UWinChemBiochem Seminar Series - Fall 2017


Prof. Tony Durst

Department of Chemistry and Biomolecular Sciences
University of Ottawa

Title: Prospecting for Natural Products in Costa Rica


Friday, October 27, 2017 @ 3:00 p.m.

Room #186 Essex Hall

**Everyone Welcome**




Abstract:
Our twenty five year long collaboration with botanists in Costa Rica has given us access to the vast plant biodiversity of Costa Rica. Joint work John Arnason (Biology) and Zul Merali (Psychology) at the University of Ottawa to enabled us to isolate novel chemical compounds and discover new applications of known entities. The seminar will focus on the development of new CYP450 inhibitors as potential insecticide synergists emanating from dillapiol isolated from Piper aduncum and the discovery of the anti-anxiety principle in Souroubea sympetala, a relatively rare Costa Rican vine. The latter work has led to a commercial product for the treatment of noise related anxiety in dogs. This product has shown excellent results in an animal model for the treatment of Post-Traumatic Stress. Health Canada approved Human Safety trials will be carried out shortly.




Friday, October 6, 2017

Tea with Lee - Thurs. Oct. 12, 2017 in 237 Essex Hall

TEA WITH DR. LEE
at 3 p.m.
Faculty of Science Boardroom, #237 Essex Hall
Thursday, October 12, 2017

***Everyone welcome***
***bring your own tea cup or mug***



2 DAY Workshop: Introduction to Practical Aspects of Solution NMR for Chemists - Oct. 11 and 12

2 DAY Workshop: Introduction to Practical Aspects of Solution NMR for Chemists - Oct. 11 and 12


2 DAY Workshop: Introduction to Practical Aspects of Solution NMR for Chemists
 
Wednesday October 11 to Thursday October 129 am to noon each day
 
This introductory workshop is geared toward undergraduate students, and new graduate students with limited NMR experience, but who are expected to make use of the NMR spectrometers as part of their research projects.

The workshop is meant as a supplement to the "one on one" training that new NMR users receive and will allow an opportunity to go into greater depth on many topics, therefore students who have recently started to use our NMR instruments are especially encouraged to attend. There will be an Advanced NMR Workshop offered later in the summer.

The schedule will consist of a lecture to start each day followed by hands-on learning sessions where participants will get the opportunity to collect and process NMR data.

The topics covered include:
  • How an NMR spectrometer works
  • NMR Magnet Safety
  • Preparation of NMR Samples
  • Set up of 1D 1H and 13C NMR Experiments
  • Processing and Presentation of NMR Data
The workshop is free of charge to members of the Dept. of Chemistry and Biochemistry; however, enrollment is limited, so please register soon!

Please note that a separate Intro Workshop will be held for MMB students in July so MMB students should not register for this workshop.

To register click here


 

Wednesday, October 4, 2017

Trivia Night - Hosted by the Grad Chem Club - Oct. 5 @ 6:30 pm

Trivia Night - Hosted by the Grad Chem Club - Oct. 5 @ 6:30 pm

Grad Chem Club presents:
TRIVIA NIGHT

Mare Nostrum Restaurant
Doors: 6:30 pm
Trivia: 7:00 pm

Entry: $2.00 per person
Prizes for top three teams!

Make team registrations by emailing: chemclub@uwindsor.ca



Thursday, September 28, 2017

Seminar: Ivan Aprahamian (Dartmouth College, NH) - Friday, September 29, 2017 @ 3:00 p.m.


Seminar: Ivan Aprahamian (Dartmouth College, NH)

UWinChemBiochem Seminar Series - Fall 2017

Prof. Ivan Aprahamian
Dartmouth College, NH
http://www.dartmouth.edu/~aprahamian/

Title: Hydrazone-Based Switches

Friday, September 29, 2017 @ 3:00 p.m.
Room #186 Essex Hall

**Everyone Welcome**


Biotechnology Entrepreneurship (BE) Symposium on Sept. 29, 2017

A Warm Invitation to the "Biotechnology Entrepreneurship” (BE) Symposium on September 29 (Friday) at the Ambassador Auditorium

It is our great pleasure to invite you to our upcoming "Biotechnology Entrepreneurship” (BE) Symposium on September 29 (Friday) at the Ambassador Auditorium, Univ. of Windsor.

We are expecting around 100 participants from Canada and United States and the target audience will be a mix of Biotechnology students, researchers and scientists, Biotechnology commercialization professionals, patent intellectuals, policy makers surrounding "Medical Marijuana" issues and grants and funding panelists.
The symposium is geared towards emerging biotechnology professionals – students with an entrepreneurial interest, future technology trend-setters and scientists who are exploring how to commercialize their discoveries (bench to market) as well as existing start-ups aiming for a sustainable future.

Below is the flyer with symposium schedule.

For more details and registration, please click: http://www.uwindsor.ca/besymp/

We look forward to seeing you there!

Kind Regards,
Tranum



Wednesday, September 20, 2017

New graduate student orientation and pizza lunch - Sept. 21 at 11 am in 273 EH

TO ALL NEW GRADUATE STUDENTS

On Thursday, September 21, 2017 at 11:00a.m. in room #273 Essex Hall, there will be a New Graduate Student orientation to provide all the information regarding the M.Sc. and Ph.D. program.  This is a mandatory meeting and all new graduate students must attend. If for some reason you can’t please come and see me. (Marlene, room #273-1).

FOR ALL GRADUATE STUDENTS, FACULTY AND STAFF IN THE DEPARTMENT OF CHEMISTRY & BIOCHEMISTRY

We will be having a Pizza lunch on Thursday, September 21, 2017 at 12:00 noon in room #273 Essex Hall.  This will be to welcome all new graduate students and enjoy some pizza.





Seminar: Yongchao Su (Merck, King of Prussia, PA) - Fri. Sep. 22, 2017 @ 2:00 p.m.

Seminar: Yongchao Su (Merck, King of Prussia, PA)

UWinChemBiochem Seminar Series - Fall 2017

Dr. Yongchao Su
Merck, King of Prussia, PA

Title: Chemical and Biophysical insights into Pharmaceutical Sciences from NMR

Friday, September 22, 2017 @ 2:00 p.m.
Room #186 Essex Hall

**Everyone Welcome**
***Note the early start time***




Wednesday, September 13, 2017

Seminar: Daniel Leznoff (SFU) - Fri. Sept. 15, 2017 @ 3:00 p.m.

UWinChemBiochem Seminar Series - Fall 2017

Prof. Daniel Leznoff
Simon Fraser University

Title: Ancient Metals in Advanced Materials:  Cyanide-based Coordination Polymers

Friday, September 15, 2017 @ 3:00 p.m.
Room #186 Essex Hall

**Everyone Welcome**


http://www.sfu.ca/leznoffgroup/